Preheat the oven as per the biscuit dough instructions.

In a bowl, mix together ground beef, cheddar cheese, cream cheese, garlic powder, onion powder, salt, and pepper until combined.

Open the biscuit dough and separate it into individual biscuits.

Place a spoonful of the beef mixture in the center of each biscuit.

Fold the biscuit around the filling to enclose it completely and pinch to seal.

Arrange the filled biscuits on a baking sheet.

Brush the tops with melted butter and sprinkle with grated Parmesan cheese.

Bake according to biscuit dough instructions or until golden brown.

Garnish with chopped parsley before serving.